![]() ![]() Haynes, who is the senior author on this project, and lead author Associate Professor Kevin Saunders, Director of Research at DHVI, built on earlier work during which they found that a patient who had been infected with SARS developed antibodies capable of neutralising not just SARS-CoV-1 but also multiple coronaviruses.Ĭoronaviruses have receptor-binding domains, located on the spike that links the viruses to receptors in human cells. Wanting to sustain the efficacy of the first mRNA vaccines against possible SARS-CoV-2 variants, DVHI set to work on a pan-coronavirus vaccine last year “This work represents a platform that could prevent, rapidly temper or extinguish a pandemic.”Ī pan-coronavirus vaccine that could protect people against new variants as well as other coronaviruses has been considered for years, but the current pandemic brought it to the forefront of many researchers’ minds. “There have been three coronavirus epidemics in the past 20 years, so there is a need to develop effective vaccines that can target these pathogens prior to the next pandemic,” said Professor Barton Haynes, Director of the DHVI. ![]() And now, the DHVI team is on the cusp of delivering just that. In other words, a vaccine that can stop future pandemics in its tracks. ![]() As the world grapples with the challenges posed by the COVID-19 pandemic, researchers at the Duke Human Vaccine Institute (DHVI) have been working round the clock in pursuit of the holy grail of vaccines: one that protects against all kinds of coronaviruses. ![]()
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